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Human m(6)A-mRNA and lncRNA epitranscriptomic microarray reveal function of RNA methylation in hemoglobin H-constant spring disease

The thalassemia of Hemoglobin H-Constant Spring disease (HbH-CS) is the most common type of Thalassemia in non-transfusion thalassemia. Interestingly, the clinical manifestations of the same genotype of thalassemia can be vastly different, likely due to epigenetic regulation. Here, we used microarra...

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Detalles Bibliográficos
Autores principales: Ruan, Heyun, Yang, Fang, Deng, Lingjie, Yang, Dongmei, Zhang, Xiaoli, Li, Xueyu, Pang, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516988/
https://www.ncbi.nlm.nih.gov/pubmed/34650160
http://dx.doi.org/10.1038/s41598-021-99867-9