Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders

The potential clinical applications of the powerful in vitro-transcribed (IVT)-mRNAs, to restore defective protein functions, strongly depend on their successful intracellular delivery and transient translation through the development of safe and efficient delivery platforms. In this study, an innov...

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Detalles Bibliográficos
Autores principales: Miliotou, Androulla N., Pappas, Ioannis S., Spyroulias, George, Vlachaki, Efthimia, Tsiftsoglou, Asterios S., Vizirianakis, Ioannis S., Papadopoulou, Lefkothea C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517095/
https://www.ncbi.nlm.nih.gov/pubmed/34703653
http://dx.doi.org/10.1016/j.omtn.2021.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517095/
https://www.ncbi.nlm.nih.gov/pubmed/34703653
http://dx.doi.org/10.1016/j.omtn.2021.09.008

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