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Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders

The potential clinical applications of the powerful in vitro-transcribed (IVT)-mRNAs, to restore defective protein functions, strongly depend on their successful intracellular delivery and transient translation through the development of safe and efficient delivery platforms. In this study, an innov...

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Detalles Bibliográficos
Autores principales:	Miliotou, Androulla N., Pappas, Ioannis S., Spyroulias, George, Vlachaki, Efthimia, Tsiftsoglou, Asterios S., Vizirianakis, Ioannis S., Papadopoulou, Lefkothea C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517095/ https://www.ncbi.nlm.nih.gov/pubmed/34703653 http://dx.doi.org/10.1016/j.omtn.2021.09.008

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