Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest

In parallel with the expansion of RNA interference (RNAi) techniques, accumulating evidence indicates that RNAi analyses might be seriously biased due to the off-target effects of gene-specific short hairpin RNAs (shRNAs). Our findings indicated that off-target effects of non-targeting shRNA compris...

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Detalles Bibliográficos
Autores principales: Czarnek, Maria, Sarad, Katarzyna, Karaś, Agnieszka, Kochan, Jakub, Bereta, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517100/
https://www.ncbi.nlm.nih.gov/pubmed/34703654
http://dx.doi.org/10.1016/j.omtn.2021.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517100/
https://www.ncbi.nlm.nih.gov/pubmed/34703654
http://dx.doi.org/10.1016/j.omtn.2021.09.004

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