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Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest
In parallel with the expansion of RNA interference (RNAi) techniques, accumulating evidence indicates that RNAi analyses might be seriously biased due to the off-target effects of gene-specific short hairpin RNAs (shRNAs). Our findings indicated that off-target effects of non-targeting shRNA compris...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517100/ https://www.ncbi.nlm.nih.gov/pubmed/34703654 http://dx.doi.org/10.1016/j.omtn.2021.09.004 |