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Analysis of signal components < 500 Hz in brain organoids coupled to microelectrode arrays: A reliable test-bed for preclinical seizure liability assessment of drugs and screening of antiepileptic drugs
Brain organoids with three-dimensional structure and tissue-like function are highly demanded for brain disease research and drug evaluation. However, to our knowledge, methods for measuring and analyzing brain organoid function have not been developed yet. This study focused on the frequency compon...
Autores principales: | Yokoi, R., Shibata, M., Odawara, A., Ishibashi, Y., Nagafuku, N., Matsuda, N., Suzuki, I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517166/ https://www.ncbi.nlm.nih.gov/pubmed/34693037 http://dx.doi.org/10.1016/j.bbrep.2021.101148 |
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