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Extracellular PKM2 facilitates organ-tissue fibrosis progression

Persistent activation of fibroblasts and resistance of myofibroblasts to turnover play important roles in organ-tissue fibrosis development and progression. The mechanism that mediates apoptosis resistance of myofibroblasts is not understood. Here, we report that myofibroblasts express and secrete P...

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Detalles Bibliográficos
Autores principales: Han, Hongwei, Zhang, Yinwei, Peng, Guangda, Li, Liangwei, Yang, Jenny, Yuan, Yi, Xu, Yiting, Liu, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517170/
https://www.ncbi.nlm.nih.gov/pubmed/34693222
http://dx.doi.org/10.1016/j.isci.2021.103165