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Extracellular PKM2 facilitates organ-tissue fibrosis progression
Persistent activation of fibroblasts and resistance of myofibroblasts to turnover play important roles in organ-tissue fibrosis development and progression. The mechanism that mediates apoptosis resistance of myofibroblasts is not understood. Here, we report that myofibroblasts express and secrete P...
Autores principales: | Han, Hongwei, Zhang, Yinwei, Peng, Guangda, Li, Liangwei, Yang, Jenny, Yuan, Yi, Xu, Yiting, Liu, Zhi-Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517170/ https://www.ncbi.nlm.nih.gov/pubmed/34693222 http://dx.doi.org/10.1016/j.isci.2021.103165 |
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