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A Conserved Structural Role for the Walker-A Lysine in P-Loop Containing Kinases
Bacterial tyrosine kinases (BY-kinases) and shikimate kinases (SKs) comprise two structurally divergent P-loop containing enzyme families that share similar catalytic site geometries, most notably with respect to their Walker-A, Walker-B, and DxD motifs. We had previously demonstrated that in BY-kin...
Autores principales: | Hajredini, Fatlum, Ghose, Ranajeet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517177/ https://www.ncbi.nlm.nih.gov/pubmed/34660698 http://dx.doi.org/10.3389/fmolb.2021.747206 |
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