Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies

Herein, we assessed the anti-inflammatory and intestinal barrier protective effects of butyrolactone-I (BTL-1), derived from the coral-derived endophytic fungus (Aspergillus terreus), using the LPS-induced IPEC-J2 inflammation model and the DSS-induced IBD model in mice. In IPEC-J2 cells, pretreatme...

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Detalles Bibliográficos
Autores principales: Chen, Shengwei, Zhang, Yi, Niu, Xueting, Mohyuddin, Sahar Ghulam, Wen, Jiayin, Bao, Minglong, Yu, Tianyue, Wu, Lianyun, Hu, Canyin, Yong, Yanhong, Liu, Xiaoxi, Abd El-Aty, A. M., Ju, Xianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517189/
https://www.ncbi.nlm.nih.gov/pubmed/34660669
http://dx.doi.org/10.3389/fnut.2021.748118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517189/
https://www.ncbi.nlm.nih.gov/pubmed/34660669
http://dx.doi.org/10.3389/fnut.2021.748118

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