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Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies
Herein, we assessed the anti-inflammatory and intestinal barrier protective effects of butyrolactone-I (BTL-1), derived from the coral-derived endophytic fungus (Aspergillus terreus), using the LPS-induced IPEC-J2 inflammation model and the DSS-induced IBD model in mice. In IPEC-J2 cells, pretreatme...
Autores principales: | Chen, Shengwei, Zhang, Yi, Niu, Xueting, Mohyuddin, Sahar Ghulam, Wen, Jiayin, Bao, Minglong, Yu, Tianyue, Wu, Lianyun, Hu, Canyin, Yong, Yanhong, Liu, Xiaoxi, Abd El-Aty, A. M., Ju, Xianghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517189/ https://www.ncbi.nlm.nih.gov/pubmed/34660669 http://dx.doi.org/10.3389/fnut.2021.748118 |
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