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Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics

The heterogeneity of respirable particulates and compounds complicates our understanding of transcriptional responses to air pollution. Here, we address this by applying precision nuclear run-on sequencing and the assay for transposase-accessible chromatin sequencing to measure nascent transcription...

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Detalles Bibliográficos
Autores principales: Gupta, Arnav, Sasse, Sarah K., Gruca, Margaret A., Sanford, Lynn, Dowell, Robin D., Gerber, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517214/
https://www.ncbi.nlm.nih.gov/pubmed/34520756
http://dx.doi.org/10.1016/j.jbc.2021.101147

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