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Directly and Indirectly Targeting the Glycine Modulatory Site to Modulate NMDA Receptor Function to Address Unmet Medical Needs of Patients With Schizophrenia

Schizophrenia is a severe mental illness that affects ~1% of the world's population. It is clinically characterized by positive, negative, and cognitive symptoms. Currently available antipsychotic medications are relatively ineffective in improving negative and cognitive deficits, which are rel...

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Detalles Bibliográficos
Autores principales: Pei, Ju-Chun, Luo, Da-Zhong, Gau, Shiang-Shin, Chang, Chia-Yuan, Lai, Wen-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517243/
https://www.ncbi.nlm.nih.gov/pubmed/34658976
http://dx.doi.org/10.3389/fpsyt.2021.742058