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Directly and Indirectly Targeting the Glycine Modulatory Site to Modulate NMDA Receptor Function to Address Unmet Medical Needs of Patients With Schizophrenia
Schizophrenia is a severe mental illness that affects ~1% of the world's population. It is clinically characterized by positive, negative, and cognitive symptoms. Currently available antipsychotic medications are relatively ineffective in improving negative and cognitive deficits, which are rel...
Autores principales: | Pei, Ju-Chun, Luo, Da-Zhong, Gau, Shiang-Shin, Chang, Chia-Yuan, Lai, Wen-Sung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517243/ https://www.ncbi.nlm.nih.gov/pubmed/34658976 http://dx.doi.org/10.3389/fpsyt.2021.742058 |
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