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The Versatile Roles of Cancer-Associated Fibroblasts in Colorectal Cancer and Therapeutic Implications

The tumor microenvironment (TME) is populated by abundant cancer-associated fibroblasts (CAFs) that radically influence the disease progression across many cancers, including the colorectal cancer (CRC). In theory, targeting CAFs holds great potential in optimizing CRC treatment. However, attempts t...

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Detalles Bibliográficos
Autores principales: Deng, Longfei, Jiang, Nianfen, Zeng, Jun, Wang, Yi, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517274/
https://www.ncbi.nlm.nih.gov/pubmed/34660589
http://dx.doi.org/10.3389/fcell.2021.733270