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Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case
Myxopapillary ependymoma (MPE) is a unique slow-growing benign (WHO grade 1) subtype of spinal cord ependymoma arising predominantly in the filum terminale. Despite its benign nature, it occasionally disseminates through the cerebrospinal fluid and metastasizes to distant sites. Here, we report an e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517289/ https://www.ncbi.nlm.nih.gov/pubmed/34691347 http://dx.doi.org/10.1016/j.radcr.2021.09.022 |
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author | Abdu, Ali M Alshoabi, Sultan A Alshoaibi, Abdulbaset M Hamid, Abdullgabbar M Jhaveri, Miral D |
author_facet | Abdu, Ali M Alshoabi, Sultan A Alshoaibi, Abdulbaset M Hamid, Abdullgabbar M Jhaveri, Miral D |
author_sort | Abdu, Ali M |
collection | PubMed |
description | Myxopapillary ependymoma (MPE) is a unique slow-growing benign (WHO grade 1) subtype of spinal cord ependymoma arising predominantly in the filum terminale. Despite its benign nature, it occasionally disseminates through the cerebrospinal fluid and metastasizes to distant sites. Here, we report an extremely rare case of MPE with interval CSF seeding and metachronous metastasis in a 47 –year-old female presented as a gradually increasing low back pain for three months with bilateral radiculopathy down to the knees. Magnetic resonance imaging (MRI) showed an intradural extramedullary spinal mass of iso-intense signal to the cord on T1 weighted-images (WIs), heterogeneous, predominantly hyperintense signal on T2WIs with homogenous enhancement after contrast administration. L2 laminectomy with gross total resection (GTR) was performed, and histopathological results confirmed the diagnosis of MPE. Adjuvant radiotherapy was administered, followed by series of MRI scans. 28 months after GTR, Lumbar MRI showed multiple tiny enhancing nodules in the cauda equina. 44 months follow-up whole spine MRI revealed multiple intradural extramedullary nodules throughout the entire spine. The largest one measures about 1.5cm opposite to T3 –T4 intervertebral disc space. The patient underwent T3 and T4 laminectomy and GTR under general anesthesia using microsurgical techniques, and the histopathological result came with the diagnosis of MPE. |
format | Online Article Text |
id | pubmed-8517289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-85172892021-10-21 Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case Abdu, Ali M Alshoabi, Sultan A Alshoaibi, Abdulbaset M Hamid, Abdullgabbar M Jhaveri, Miral D Radiol Case Rep Case Report Myxopapillary ependymoma (MPE) is a unique slow-growing benign (WHO grade 1) subtype of spinal cord ependymoma arising predominantly in the filum terminale. Despite its benign nature, it occasionally disseminates through the cerebrospinal fluid and metastasizes to distant sites. Here, we report an extremely rare case of MPE with interval CSF seeding and metachronous metastasis in a 47 –year-old female presented as a gradually increasing low back pain for three months with bilateral radiculopathy down to the knees. Magnetic resonance imaging (MRI) showed an intradural extramedullary spinal mass of iso-intense signal to the cord on T1 weighted-images (WIs), heterogeneous, predominantly hyperintense signal on T2WIs with homogenous enhancement after contrast administration. L2 laminectomy with gross total resection (GTR) was performed, and histopathological results confirmed the diagnosis of MPE. Adjuvant radiotherapy was administered, followed by series of MRI scans. 28 months after GTR, Lumbar MRI showed multiple tiny enhancing nodules in the cauda equina. 44 months follow-up whole spine MRI revealed multiple intradural extramedullary nodules throughout the entire spine. The largest one measures about 1.5cm opposite to T3 –T4 intervertebral disc space. The patient underwent T3 and T4 laminectomy and GTR under general anesthesia using microsurgical techniques, and the histopathological result came with the diagnosis of MPE. Elsevier 2021-10-10 /pmc/articles/PMC8517289/ /pubmed/34691347 http://dx.doi.org/10.1016/j.radcr.2021.09.022 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Abdu, Ali M Alshoabi, Sultan A Alshoaibi, Abdulbaset M Hamid, Abdullgabbar M Jhaveri, Miral D Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title | Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title_full | Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title_fullStr | Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title_full_unstemmed | Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title_short | Myxopapillary ependymoma with interval postoperative CSF seeding: A report of an unusual case |
title_sort | myxopapillary ependymoma with interval postoperative csf seeding: a report of an unusual case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517289/ https://www.ncbi.nlm.nih.gov/pubmed/34691347 http://dx.doi.org/10.1016/j.radcr.2021.09.022 |
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