Cargando…
Physiologic and molecular characterization of a novel murine model of metastatic head and neck cancer cachexia
BACKGROUND: Cancer cachexia is a metabolic disorder characterized by the progressive loss of fat and lean mass that results in significant wasting, ultimately leading to reduced quality of life and increased mortality. Effective therapies for cachexia are lacking, potentially owing to the mismatch i...
Autores principales: | Olson, Brennan, Norgard, Mason A., Levasseur, Peter R., Zhu, Xinxia, Marks, Daniel L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517353/ https://www.ncbi.nlm.nih.gov/pubmed/34231343 http://dx.doi.org/10.1002/jcsm.12745 |
Ejemplares similares
-
Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer
por: Burfeind, Kevin G., et al.
Publicado: (2020) -
Establishment and characterization of a novel murine model of pancreatic cancer cachexia
por: Michaelis, Katherine A., et al.
Publicado: (2017) -
Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia
por: Olson, Brennan, et al.
Publicado: (2021) -
Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer
por: Burfeind, Kevin G, et al.
Publicado: (2020) -
Lipopolysaccharide‐induced hypothalamic inflammation in cancer cachexia‐anorexia is amplified by tumour‐derived prostaglandin E2
por: Li, Xiaolin, et al.
Publicado: (2022)