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Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation

OBJECTIVES: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and be...

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Autores principales: Chang, Yeonhwa, Kim, Chanhee, Kim, Nayoung, Kim, Joon Jai, Lee, Heeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Preventive Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517365/
https://www.ncbi.nlm.nih.gov/pubmed/34649399
http://dx.doi.org/10.3961/jpmph.21.349
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author Chang, Yeonhwa
Kim, Chanhee
Kim, Nayoung
Kim, Joon Jai
Lee, Heeyoung
author_facet Chang, Yeonhwa
Kim, Chanhee
Kim, Nayoung
Kim, Joon Jai
Lee, Heeyoung
author_sort Chang, Yeonhwa
collection PubMed
description OBJECTIVES: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and between generally abled and disabled groups. METHODS: We analyzed the incubation period and attack rate of an HAV outbreak and investigated the prevalence of HAV antibodies among the staff and residents of a facility for the disabled. We performed a retrospective cohort study during the HAV outbreak, which lasted from February 8 to 25, 2019, including examinations of HAV antibody tests and post-exposure HAV vaccination for the staff or residents of the facility. RESULTS: There were 9 confirmed cases in 2 staff members and 7 residents. Among 53 people (30 staff and 23 residents), except for the 9 confirmed cases and 1 staff member with a known history of HAV infection, HAV seroprevalence was seen in 16.7% of the staff under 40 years of age and 95.2% of those over 40 years of age, while the corresponding rates in the residents were 0.0% and 58.8%, respectively. CONCLUSIONS: This result implies that it is necessary to prioritize HAV vaccination for vulnerable groups and workers of residential care facilities.
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spelling pubmed-85173652021-10-26 Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation Chang, Yeonhwa Kim, Chanhee Kim, Nayoung Kim, Joon Jai Lee, Heeyoung J Prev Med Public Health Original Article OBJECTIVES: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and between generally abled and disabled groups. METHODS: We analyzed the incubation period and attack rate of an HAV outbreak and investigated the prevalence of HAV antibodies among the staff and residents of a facility for the disabled. We performed a retrospective cohort study during the HAV outbreak, which lasted from February 8 to 25, 2019, including examinations of HAV antibody tests and post-exposure HAV vaccination for the staff or residents of the facility. RESULTS: There were 9 confirmed cases in 2 staff members and 7 residents. Among 53 people (30 staff and 23 residents), except for the 9 confirmed cases and 1 staff member with a known history of HAV infection, HAV seroprevalence was seen in 16.7% of the staff under 40 years of age and 95.2% of those over 40 years of age, while the corresponding rates in the residents were 0.0% and 58.8%, respectively. CONCLUSIONS: This result implies that it is necessary to prioritize HAV vaccination for vulnerable groups and workers of residential care facilities. Korean Society for Preventive Medicine 2021-09 2021-09-02 /pmc/articles/PMC8517365/ /pubmed/34649399 http://dx.doi.org/10.3961/jpmph.21.349 Text en Copyright © 2021 The Korean Society for Preventive Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Chang, Yeonhwa
Kim, Chanhee
Kim, Nayoung
Kim, Joon Jai
Lee, Heeyoung
Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title_full Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title_fullStr Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title_full_unstemmed Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title_short Hepatitis A Outbreak in a Facility for the Disabled, Gyeonggi Province, Korea: An Epidemiological Investigation
title_sort hepatitis a outbreak in a facility for the disabled, gyeonggi province, korea: an epidemiological investigation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517365/
https://www.ncbi.nlm.nih.gov/pubmed/34649399
http://dx.doi.org/10.3961/jpmph.21.349
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