Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in collagen fibers. Type VIII collagen (Col-8) is highly expressed developmentally,...

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Detalles Bibliográficos
Autores principales: Mohabeer, Amanda L., Kroetsch, Jeffrey T., McFadden, Meghan, Khosraviani, Negin, Broekelmann, Thomas J., Hou, Guangpei, Zhang, Hangjun, Zhou, Yu-Qing, Wang, Minyao, Gramolini, Anthony O., Mecham, Robert P., Heximer, Scott P., Bolz, Steffen-Sebastian, Bendeck, Michelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517381/
https://www.ncbi.nlm.nih.gov/pubmed/34693248
http://dx.doi.org/10.1016/j.mbplus.2021.100085

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