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DNA Repair and Immune Response Pathways Are Deregulated in Melanocyte-Keratinocyte Co-cultures Derived From the Healthy Skin of Familial Melanoma Patients
Familial melanoma accounts for 10% of cases, being CDKN2A the main high-risk gene. However, the mechanisms underlying melanomagenesis in these cases remain poorly understood. Our aim was to analyze the transcriptome of melanocyte-keratinocyte co-cultures derived from healthy skin from familial melan...
Autores principales: | Potrony, Miriam, Haddad, Tariq Sami, Tell-Martí, Gemma, Gimenez-Xavier, Pol, Leon, Carlos, Pevida, Marta, Mateu, Judit, Badenas, Celia, Carrera, Cristina, Malvehy, Josep, Aguilera, Paula, Llames, Sara, Escámez, Maria José, Puig-Butillé, Joan A., del Río, Marcela, Puig, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517393/ https://www.ncbi.nlm.nih.gov/pubmed/34660619 http://dx.doi.org/10.3389/fmed.2021.692341 |
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