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XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1α-Dependent Decay

Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective therapeutic procedure to treat hematological malignancies. However, the benefit of allo-HCT is limited by a major complication, chronic graft-versus-host disease (cGVHD). Since transmembrane and secretory proteins are generated...

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Detalles Bibliográficos
Autores principales:	Choi, Hee-Jin, Tang, Chih-Hang Anthony, Tian, Linlu, Wu, Yongxia, Sofi, M. Hanief, Ticer, Taylor, Schutt, Steven D., Hu, Chih-Chi Andrew, Yu, Xue-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517405/ https://www.ncbi.nlm.nih.gov/pubmed/34659198 http://dx.doi.org/10.3389/fimmu.2021.705484

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