A New Human Leukocyte Antigen Typing Algorithm Combined With Currently Available Genotyping Tools Based on Next-Generation Sequencing Data and Guidelines to Select the Most Likely Human Leukocyte Antigen Genotype

BACKGROUND: High-precision human leukocyte antigen (HLA) genotyping is crucial for anti-cancer immunotherapy, but existing tools predicting HLA genotypes using next-generation sequencing (NGS) data are insufficiently accurate. MATERIALS AND METHODS: We compared availability, accuracy, correction sco...

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Detalles Bibliográficos
Autores principales: Lee, Miseon, Seo, Jeong-Han, Song, Sungjae, Song, In Hye, Kim, Su Yeon, Kim, Young-Ae, Gong, Gyungyub, Kim, Jeong Eun, Lee, Hee Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517438/
https://www.ncbi.nlm.nih.gov/pubmed/34659196
http://dx.doi.org/10.3389/fimmu.2021.688183

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