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4-Hydroxy-2-Nonenal Promotes Cardiomyocyte Necroptosis via Stabilizing Receptor-Interacting Serine/Threonine-Protein Kinase 1

Background: Necroptosis is a vital regulator of myocardial ischemia/reperfusion (MI/R) injury. Meanwhile, 4-hydroxy-2-nonenal (4-HNE) is abundantly increased during MI/R injury. However, whether 4-HNE induces cardiomyocyte necroptosis during MI/R remains unknown. Methods: To observe the relationship...

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Detalles Bibliográficos
Autores principales:	Zhai, Xiaoxuan, Wang, Wenjun, Sun, Shukun, Han, Yu, Li, Jiaxin, Cao, Shengchuan, Li, Ruochuan, Xu, Tonghui, Yuan, Qiuhuan, Wang, Jiali, Wei, Shujian, Chen, Yuguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517475/ https://www.ncbi.nlm.nih.gov/pubmed/34660582 http://dx.doi.org/10.3389/fcell.2021.721795

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