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Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway

There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers w...

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Detalles Bibliográficos
Autores principales: SÜER, N. Ceren, ARASOĞLU, Tülin, CANKURTARAN, Hüsnü, OKUTAN, Mustafa, GALLEI, Markus, EREN, Tarik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517495/
https://www.ncbi.nlm.nih.gov/pubmed/34707429
http://dx.doi.org/10.3906/kim-2012-14
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author SÜER, N. Ceren
ARASOĞLU, Tülin
CANKURTARAN, Hüsnü
OKUTAN, Mustafa
GALLEI, Markus
EREN, Tarik
author_facet SÜER, N. Ceren
ARASOĞLU, Tülin
CANKURTARAN, Hüsnü
OKUTAN, Mustafa
GALLEI, Markus
EREN, Tarik
author_sort SÜER, N. Ceren
collection PubMed
description There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers were synthesized, and their biocidal activities were tested on the glass surface. Interdigitated electrode arrays coated with the polymers possessing the highest activity were used to screen the affinity towards different bacterial strains by monitoring impedance variations in real-time. The polymer-coated electrode could detect gram-positive and gram-negative bacteria strains at a concentration of 10(7 )cfu/mL. The results show that ROMP-based polymer offers bacterial detection and can be used in developing biosensor devices for efficiently detecting pathogenic bacteria.
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spelling pubmed-85174952021-10-26 Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway SÜER, N. Ceren ARASOĞLU, Tülin CANKURTARAN, Hüsnü OKUTAN, Mustafa GALLEI, Markus EREN, Tarik Turk J Chem Article There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers were synthesized, and their biocidal activities were tested on the glass surface. Interdigitated electrode arrays coated with the polymers possessing the highest activity were used to screen the affinity towards different bacterial strains by monitoring impedance variations in real-time. The polymer-coated electrode could detect gram-positive and gram-negative bacteria strains at a concentration of 10(7 )cfu/mL. The results show that ROMP-based polymer offers bacterial detection and can be used in developing biosensor devices for efficiently detecting pathogenic bacteria. The Scientific and Technological Research Council of Turkey 2021-08-27 /pmc/articles/PMC8517495/ /pubmed/34707429 http://dx.doi.org/10.3906/kim-2012-14 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
SÜER, N. Ceren
ARASOĞLU, Tülin
CANKURTARAN, Hüsnü
OKUTAN, Mustafa
GALLEI, Markus
EREN, Tarik
Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title_full Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title_fullStr Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title_full_unstemmed Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title_short Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
title_sort detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517495/
https://www.ncbi.nlm.nih.gov/pubmed/34707429
http://dx.doi.org/10.3906/kim-2012-14
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