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Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific and Technological Research Council of Turkey
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517495/ https://www.ncbi.nlm.nih.gov/pubmed/34707429 http://dx.doi.org/10.3906/kim-2012-14 |
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author | SÜER, N. Ceren ARASOĞLU, Tülin CANKURTARAN, Hüsnü OKUTAN, Mustafa GALLEI, Markus EREN, Tarik |
author_facet | SÜER, N. Ceren ARASOĞLU, Tülin CANKURTARAN, Hüsnü OKUTAN, Mustafa GALLEI, Markus EREN, Tarik |
author_sort | SÜER, N. Ceren |
collection | PubMed |
description | There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers were synthesized, and their biocidal activities were tested on the glass surface. Interdigitated electrode arrays coated with the polymers possessing the highest activity were used to screen the affinity towards different bacterial strains by monitoring impedance variations in real-time. The polymer-coated electrode could detect gram-positive and gram-negative bacteria strains at a concentration of 10(7 )cfu/mL. The results show that ROMP-based polymer offers bacterial detection and can be used in developing biosensor devices for efficiently detecting pathogenic bacteria. |
format | Online Article Text |
id | pubmed-8517495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Scientific and Technological Research Council of Turkey |
record_format | MEDLINE/PubMed |
spelling | pubmed-85174952021-10-26 Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway SÜER, N. Ceren ARASOĞLU, Tülin CANKURTARAN, Hüsnü OKUTAN, Mustafa GALLEI, Markus EREN, Tarik Turk J Chem Article There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers were synthesized, and their biocidal activities were tested on the glass surface. Interdigitated electrode arrays coated with the polymers possessing the highest activity were used to screen the affinity towards different bacterial strains by monitoring impedance variations in real-time. The polymer-coated electrode could detect gram-positive and gram-negative bacteria strains at a concentration of 10(7 )cfu/mL. The results show that ROMP-based polymer offers bacterial detection and can be used in developing biosensor devices for efficiently detecting pathogenic bacteria. The Scientific and Technological Research Council of Turkey 2021-08-27 /pmc/articles/PMC8517495/ /pubmed/34707429 http://dx.doi.org/10.3906/kim-2012-14 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Article SÜER, N. Ceren ARASOĞLU, Tülin CANKURTARAN, Hüsnü OKUTAN, Mustafa GALLEI, Markus EREN, Tarik Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title | Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title_full | Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title_fullStr | Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title_full_unstemmed | Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title_short | Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
title_sort | detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517495/ https://www.ncbi.nlm.nih.gov/pubmed/34707429 http://dx.doi.org/10.3906/kim-2012-14 |
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