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Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH(2) Through Ultrasound to Enhance the Antitumor Efficacy and Attenuate the Toxicity for Treatment of Malignant Glioma

BACKGROUND: Glioma is the most common and malignant primary brain tumour in adults and has a dismal prognosis. Temozolomide (TMZ) is the only clinical first-line chemotherapy drug for malignant glioma up to present. Due to poor aqueous solubility and toxic effects, TMZ is still inefficient and limit...

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Detalles Bibliográficos
Autores principales:	Wan, Zhiping, Li, Chunlin, Gu, Jinmao, Qian, Jun, Zhu, Junle, Wang, Jiaqi, Li, Yinwen, Jiang, Jiahao, Chen, Huairui, Luo, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517532/ https://www.ncbi.nlm.nih.gov/pubmed/34675514 http://dx.doi.org/10.2147/IJN.S330187

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