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Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt

The opportunistic infection of post-Covid associated mucormycosis has been reported globally; however, it has reached alarming proportions in India. Mucormycosis of the mandibular region is rare, and only a few cases have been reported to date. Covid associated mucormycosis has not been reported in...

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Autores principales: Dasukil, Saubhik, Boyina, Kiran Kumar, Sarkar, Saurav, Hallur, Vinaykumar, Nayak, Anindya, Mishra, Abhijeet Kumar, Aswathi, KV, Preetam, Chappity, Parida, Pradipta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517559/
https://www.ncbi.nlm.nih.gov/pubmed/34667749
http://dx.doi.org/10.1007/s12070-021-02925-x
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author Dasukil, Saubhik
Boyina, Kiran Kumar
Sarkar, Saurav
Hallur, Vinaykumar
Nayak, Anindya
Mishra, Abhijeet Kumar
Aswathi, KV
Preetam, Chappity
Parida, Pradipta Kumar
author_facet Dasukil, Saubhik
Boyina, Kiran Kumar
Sarkar, Saurav
Hallur, Vinaykumar
Nayak, Anindya
Mishra, Abhijeet Kumar
Aswathi, KV
Preetam, Chappity
Parida, Pradipta Kumar
author_sort Dasukil, Saubhik
collection PubMed
description The opportunistic infection of post-Covid associated mucormycosis has been reported globally; however, it has reached alarming proportions in India. Mucormycosis of the mandibular region is rare, and only a few cases have been reported to date. Covid associated mucormycosis has not been reported in the literature before, and we are the first to report them. We report two patients who presented with tooth loosening with pus discharge a few weeks following recovery from Covid infection. After tooth extraction adjacent necrotic bony specimen was sent for calcofluor potassium hydroxide mount, which was found positive for broad pauciseptate hyphae. Although CT scan imaging demonstrated the involvement of a mandible segment, we found a much more extensive involvement in both cases during resection. There was intramedullary spread of the mucormycosis throughout the inferior alveolar canal, with pus discharge and foul odor. The management of covid associated mandibular mucormycosis consists of surgical debridement with antifungal therapy and control of the underlying disease. It became challenging because the radiological extent of the disease was different from the definite clinical extension of the lesion found during surgery. The authors recommend surgeons adopt a flexible approach during surgery to plan resection depending on the clinical judgment and not rely entirely on CT scans. And the reconstruction of the mandible will follow as per the extent of excision.
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spelling pubmed-85175592021-10-15 Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt Dasukil, Saubhik Boyina, Kiran Kumar Sarkar, Saurav Hallur, Vinaykumar Nayak, Anindya Mishra, Abhijeet Kumar Aswathi, KV Preetam, Chappity Parida, Pradipta Kumar Indian J Otolaryngol Head Neck Surg Clinical Report The opportunistic infection of post-Covid associated mucormycosis has been reported globally; however, it has reached alarming proportions in India. Mucormycosis of the mandibular region is rare, and only a few cases have been reported to date. Covid associated mucormycosis has not been reported in the literature before, and we are the first to report them. We report two patients who presented with tooth loosening with pus discharge a few weeks following recovery from Covid infection. After tooth extraction adjacent necrotic bony specimen was sent for calcofluor potassium hydroxide mount, which was found positive for broad pauciseptate hyphae. Although CT scan imaging demonstrated the involvement of a mandible segment, we found a much more extensive involvement in both cases during resection. There was intramedullary spread of the mucormycosis throughout the inferior alveolar canal, with pus discharge and foul odor. The management of covid associated mandibular mucormycosis consists of surgical debridement with antifungal therapy and control of the underlying disease. It became challenging because the radiological extent of the disease was different from the definite clinical extension of the lesion found during surgery. The authors recommend surgeons adopt a flexible approach during surgery to plan resection depending on the clinical judgment and not rely entirely on CT scans. And the reconstruction of the mandible will follow as per the extent of excision. Springer India 2021-10-15 2022-10 /pmc/articles/PMC8517559/ /pubmed/34667749 http://dx.doi.org/10.1007/s12070-021-02925-x Text en © Association of Otolaryngologists of India 2021
spellingShingle Clinical Report
Dasukil, Saubhik
Boyina, Kiran Kumar
Sarkar, Saurav
Hallur, Vinaykumar
Nayak, Anindya
Mishra, Abhijeet Kumar
Aswathi, KV
Preetam, Chappity
Parida, Pradipta Kumar
Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title_full Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title_fullStr Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title_full_unstemmed Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title_short Management of Covid Associated Mucormycosis of Mandible: A Mountain Beneath a Molehill—A Lesson Learnt
title_sort management of covid associated mucormycosis of mandible: a mountain beneath a molehill—a lesson learnt
topic Clinical Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517559/
https://www.ncbi.nlm.nih.gov/pubmed/34667749
http://dx.doi.org/10.1007/s12070-021-02925-x
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