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Distinct antigen uptake receptors route to the same storage compartments for cross‐presentation in dendritic cells

An exclusive feature of dendritic cells (DCs) is their capacity to present exogenous antigens by MHC class I molecules, called cross‐presentation. Here, we show that protein antigen can be conserved in mature murine DCs for several days in a lysosome‐like storage compartment, distinct from MHC class...

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Detalles Bibliográficos
Autores principales: Ho, Nataschja I., Camps, Marcel G., Garcia‐Vallejo, Juan J., Bos, Erik, Koster, Abraham J., Verdoes, Martijn, van Kooyk, Yvette, Ossendorp, Ferry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517591/
https://www.ncbi.nlm.nih.gov/pubmed/34110622
http://dx.doi.org/10.1111/imm.13382