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Distinct antigen uptake receptors route to the same storage compartments for cross‐presentation in dendritic cells
An exclusive feature of dendritic cells (DCs) is their capacity to present exogenous antigens by MHC class I molecules, called cross‐presentation. Here, we show that protein antigen can be conserved in mature murine DCs for several days in a lysosome‐like storage compartment, distinct from MHC class...
Autores principales: | Ho, Nataschja I., Camps, Marcel G., Garcia‐Vallejo, Juan J., Bos, Erik, Koster, Abraham J., Verdoes, Martijn, van Kooyk, Yvette, Ossendorp, Ferry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517591/ https://www.ncbi.nlm.nih.gov/pubmed/34110622 http://dx.doi.org/10.1111/imm.13382 |
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