ATP/IL‐33‐triggered hyperactivation of mast cells results in an amplified production of pro‐inflammatory cytokines and eicosanoids

IL‐33 and ATP are alarmins, which are released upon damage of cellular barriers or are actively secreted upon cell stress. Due to high‐density expression of the IL‐33 receptor T1/ST2 (IL‐33R), and the ATP receptor P2X7, mast cells (MCs) are one of the first highly sensitive sentinels recognizing rel...

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Detalles Bibliográficos
Autores principales: Jordan, Paul M., Andreas, Nico, Groth, Marco, Wegner, Philine, Weber, Franziska, Jäger, Ute, Küchler, Claudia, Werz, Oliver, Serfling, Edgar, Kamradt, Thomas, Dudeck, Anne, Drube, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517600/
https://www.ncbi.nlm.nih.gov/pubmed/34142370
http://dx.doi.org/10.1111/imm.13386

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