Calcium channels and iron metabolism: A redox catastrophe in Parkinson's disease and an innovative path to novel therapies?

Autonomously spiking dopaminergic neurons of the substantia nigra pars compacta (SNpc) are exquisitely specialized and suffer toxic iron-loading in Parkinson's disease (PD). However, the molecular mechanism involved remains unclear and critical to decipher for designing new PD therapeutics. The...

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Detalles Bibliográficos
Autores principales: Boag, Matthew K., Ma, Linlin, Mellick, George D., Pountney, Dean L., Feng, Yunjiang, Quinn, Ronald J., Liew, Alan Wee-Chung, Dharmasivam, Mahendiran, Azad, Mahan Gholam, Afroz, Rizwana, Richardson, Des R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517601/
https://www.ncbi.nlm.nih.gov/pubmed/34653841
http://dx.doi.org/10.1016/j.redox.2021.102136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517601/
https://www.ncbi.nlm.nih.gov/pubmed/34653841
http://dx.doi.org/10.1016/j.redox.2021.102136

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