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Metastatic atypical renal tumour with metanephric characteristics treated with Sunitinib

Metanephric Adenoma (MA) is a rare and unclassifiable renal tumour with sparse reported clinical and morphological features. Generally MA's have a benign course without recurrence after nephrectomy, however a few cases received oncological treatment due to malignant progression. We present a 42...

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Detalles Bibliográficos
Autores principales: Mohammad, H., Madsen, K., Graumann, O., Loya, A.C., Jensen, N.V., Dahlrot, R.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517833/
https://www.ncbi.nlm.nih.gov/pubmed/34692420
http://dx.doi.org/10.1016/j.eucr.2021.101880
Descripción
Sumario:Metanephric Adenoma (MA) is a rare and unclassifiable renal tumour with sparse reported clinical and morphological features. Generally MA's have a benign course without recurrence after nephrectomy, however a few cases received oncological treatment due to malignant progression. We present a 42-year-old woman who years after an initial nephrectomy developed several processes and biopsy confirmed recurrence of MA. Sunitinib was given for only two weeks, as she developed side-effects and currently the patient undergoes control scans with only minimal growth of the processes. This is the first case of MA treated with Tyrosin-Kinase-Inhibitor.