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Elimination of cephalexin and doxycycline under low frequency ultrasound
Cephalexin (CPX) and doxycycline (DOX) are two of the most used antibiotics to treat bacterial infections in human medicine, veterinary practices, animal husbandry, agriculture, aquaculture, among others. Nevertheless, due to their excessive consumption and incomplete absorption during their metabol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517921/ https://www.ncbi.nlm.nih.gov/pubmed/34649167 http://dx.doi.org/10.1016/j.ultsonch.2021.105777 |
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author | Cárdenas Sierra, Rafael Santiago Zúñiga-Benítez, Henry Peñuela, Gustavo A. |
author_facet | Cárdenas Sierra, Rafael Santiago Zúñiga-Benítez, Henry Peñuela, Gustavo A. |
author_sort | Cárdenas Sierra, Rafael Santiago |
collection | PubMed |
description | Cephalexin (CPX) and doxycycline (DOX) are two of the most used antibiotics to treat bacterial infections in human medicine, veterinary practices, animal husbandry, agriculture, aquaculture, among others. Nevertheless, due to their excessive consumption and incomplete absorption during their metabolization, they have been detected in different environmental matrices and the effluents of wastewater treatment plants, which reflects that conventional water treatment methods are not enough to eliminate this type of compounds. This paper presents the main results about the removal of the antibiotics CPX and DOX under low frequency (40 kHz) ultrasonic radiation (US). The effects of operational parameters such as the solution initial pH and the applied US power were assessed considering the response surface methodology and a face centered, central composite experimental design. The results indicated that evaluated operational factors significantly affect the pollutants elimination and that US technology is able to remove them completely. In addition, in terms of mineralization, experimental results showed a reduction of the organic carbon present in the solutions and a significant increase of ions (nitrates and sulfates) concentration, suggesting that part of the organic matter was transformed into CO(2), H(2)O and inorganic species. Finally, results regarding the samples toxicity indicated that ultrasonic treatment could promote a significant reduction in this parameter, and the potential negative effect associated to CPX and DOX presence in water bodies. |
format | Online Article Text |
id | pubmed-8517921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-85179212021-10-21 Elimination of cephalexin and doxycycline under low frequency ultrasound Cárdenas Sierra, Rafael Santiago Zúñiga-Benítez, Henry Peñuela, Gustavo A. Ultrason Sonochem Review Article Cephalexin (CPX) and doxycycline (DOX) are two of the most used antibiotics to treat bacterial infections in human medicine, veterinary practices, animal husbandry, agriculture, aquaculture, among others. Nevertheless, due to their excessive consumption and incomplete absorption during their metabolization, they have been detected in different environmental matrices and the effluents of wastewater treatment plants, which reflects that conventional water treatment methods are not enough to eliminate this type of compounds. This paper presents the main results about the removal of the antibiotics CPX and DOX under low frequency (40 kHz) ultrasonic radiation (US). The effects of operational parameters such as the solution initial pH and the applied US power were assessed considering the response surface methodology and a face centered, central composite experimental design. The results indicated that evaluated operational factors significantly affect the pollutants elimination and that US technology is able to remove them completely. In addition, in terms of mineralization, experimental results showed a reduction of the organic carbon present in the solutions and a significant increase of ions (nitrates and sulfates) concentration, suggesting that part of the organic matter was transformed into CO(2), H(2)O and inorganic species. Finally, results regarding the samples toxicity indicated that ultrasonic treatment could promote a significant reduction in this parameter, and the potential negative effect associated to CPX and DOX presence in water bodies. Elsevier 2021-10-07 /pmc/articles/PMC8517921/ /pubmed/34649167 http://dx.doi.org/10.1016/j.ultsonch.2021.105777 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Cárdenas Sierra, Rafael Santiago Zúñiga-Benítez, Henry Peñuela, Gustavo A. Elimination of cephalexin and doxycycline under low frequency ultrasound |
title | Elimination of cephalexin and doxycycline under low frequency ultrasound |
title_full | Elimination of cephalexin and doxycycline under low frequency ultrasound |
title_fullStr | Elimination of cephalexin and doxycycline under low frequency ultrasound |
title_full_unstemmed | Elimination of cephalexin and doxycycline under low frequency ultrasound |
title_short | Elimination of cephalexin and doxycycline under low frequency ultrasound |
title_sort | elimination of cephalexin and doxycycline under low frequency ultrasound |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517921/ https://www.ncbi.nlm.nih.gov/pubmed/34649167 http://dx.doi.org/10.1016/j.ultsonch.2021.105777 |
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