Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor

[Image: see text] Single-molecule measurements provide detailed mechanistic insights into molecular processes, for example in genome regulation where DNA access is controlled by nucleosomes and the chromatin machinery. However, real-time single-molecule observations of nuclear factors acting on defi...

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Detalles Bibliográficos
Autores principales: Makasheva, Kristina, Bryan, Louise C., Anders, Carolin, Panikulam, Sherin, Jinek, Martin, Fierz, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517959/
https://www.ncbi.nlm.nih.gov/pubmed/34597515
http://dx.doi.org/10.1021/jacs.1c06195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517959/
https://www.ncbi.nlm.nih.gov/pubmed/34597515
http://dx.doi.org/10.1021/jacs.1c06195

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