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Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review

BACKGROUND: Prelamination is a reconstructive technique providing fasciomucosal or composite flaps with low donor‐site morbidity. We conducted a systematic review of retrospective studies to assess the application of prelaminated flaps in reconstructive surgery of head and neck cancer patients, and...

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Autores principales: Fermi, Matteo, Bassano, Edoardo, Molinari, Giulia, Alicandri‐Ciufelli, Matteo, Scarpa, Alfonso, Presutti, Livio, De Santis, Giorgio, Mattioli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518088/
https://www.ncbi.nlm.nih.gov/pubmed/33960527
http://dx.doi.org/10.1002/micr.30751
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author Fermi, Matteo
Bassano, Edoardo
Molinari, Giulia
Alicandri‐Ciufelli, Matteo
Scarpa, Alfonso
Presutti, Livio
De Santis, Giorgio
Mattioli, Francesco
author_facet Fermi, Matteo
Bassano, Edoardo
Molinari, Giulia
Alicandri‐Ciufelli, Matteo
Scarpa, Alfonso
Presutti, Livio
De Santis, Giorgio
Mattioli, Francesco
author_sort Fermi, Matteo
collection PubMed
description BACKGROUND: Prelamination is a reconstructive technique providing fasciomucosal or composite flaps with low donor‐site morbidity. We conducted a systematic review of retrospective studies to assess the application of prelaminated flaps in reconstructive surgery of head and neck cancer patients, and to evaluate the advantages and disadvantages of this technique. METHODS: This systematic review adhered to the recommendations of the PRISMA (Preferred Reporting Items of Systematic Reviews and Meta‐analysis) 2009 guidelines. A computerized MEDLINE search was performed using the PubMed service of the U.S. National Library of Medicine (www.pubmed.org) and Scopus database (www.scopus.com), running the following search string: “prelamination OR prelaminated AND flap.” Two authors screened the articles, then selected and extracted data on malignancies characteristics, reconstructive techniques, outcomes and complications. RESULTS: A total of 19 articles were selected and reviewed from 128 identified. Seven of 19 articles were case reports, 12 articles were case series. One‐hundred‐two patients underwent reconstructive treatment by prelamination technique using a wide variety of flaps (92 free, 10 pedicled). The sites of reconstruction were oral cavity (66 floor of the mouth, 3 retromolar trigone, 6 hard palate, 4 cheek, 4 tongue), 8 facial skin (5 of them sited on the nose), 4 oropharyngeal defects, 1 laryngotracheal region. No case of total flap loss was reported. Partial flap loss or shrinkage requiring minor surgical revisions was observed in 18 patients (17.6%). Primary closure of the donor site was achieved in 97 cases (97%) and 3 (3%) required revision surgery of the donor site. CONCLUSION: Prelamination is an effective and versatile technique, with low donor‐site morbidity. Further studies would be needed to investigate the impact on the patient's oncologic outcome. More comparative studies with standard reconstructive techniques are essential to understand when it is worth performing this sophisticated procedure.
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spelling pubmed-85180882021-10-21 Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review Fermi, Matteo Bassano, Edoardo Molinari, Giulia Alicandri‐Ciufelli, Matteo Scarpa, Alfonso Presutti, Livio De Santis, Giorgio Mattioli, Francesco Microsurgery Review Article BACKGROUND: Prelamination is a reconstructive technique providing fasciomucosal or composite flaps with low donor‐site morbidity. We conducted a systematic review of retrospective studies to assess the application of prelaminated flaps in reconstructive surgery of head and neck cancer patients, and to evaluate the advantages and disadvantages of this technique. METHODS: This systematic review adhered to the recommendations of the PRISMA (Preferred Reporting Items of Systematic Reviews and Meta‐analysis) 2009 guidelines. A computerized MEDLINE search was performed using the PubMed service of the U.S. National Library of Medicine (www.pubmed.org) and Scopus database (www.scopus.com), running the following search string: “prelamination OR prelaminated AND flap.” Two authors screened the articles, then selected and extracted data on malignancies characteristics, reconstructive techniques, outcomes and complications. RESULTS: A total of 19 articles were selected and reviewed from 128 identified. Seven of 19 articles were case reports, 12 articles were case series. One‐hundred‐two patients underwent reconstructive treatment by prelamination technique using a wide variety of flaps (92 free, 10 pedicled). The sites of reconstruction were oral cavity (66 floor of the mouth, 3 retromolar trigone, 6 hard palate, 4 cheek, 4 tongue), 8 facial skin (5 of them sited on the nose), 4 oropharyngeal defects, 1 laryngotracheal region. No case of total flap loss was reported. Partial flap loss or shrinkage requiring minor surgical revisions was observed in 18 patients (17.6%). Primary closure of the donor site was achieved in 97 cases (97%) and 3 (3%) required revision surgery of the donor site. CONCLUSION: Prelamination is an effective and versatile technique, with low donor‐site morbidity. Further studies would be needed to investigate the impact on the patient's oncologic outcome. More comparative studies with standard reconstructive techniques are essential to understand when it is worth performing this sophisticated procedure. John Wiley & Sons, Inc. 2021-05-07 2021-09 /pmc/articles/PMC8518088/ /pubmed/33960527 http://dx.doi.org/10.1002/micr.30751 Text en © 2021 The Authors. Microsurgery published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Article
Fermi, Matteo
Bassano, Edoardo
Molinari, Giulia
Alicandri‐Ciufelli, Matteo
Scarpa, Alfonso
Presutti, Livio
De Santis, Giorgio
Mattioli, Francesco
Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title_full Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title_fullStr Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title_full_unstemmed Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title_short Prelaminated flaps in head and neck cancer reconstructive surgery: A systematic review
title_sort prelaminated flaps in head and neck cancer reconstructive surgery: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518088/
https://www.ncbi.nlm.nih.gov/pubmed/33960527
http://dx.doi.org/10.1002/micr.30751
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