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Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects

AIMS: Emodepside is an anthelmintic, originally developed for veterinary use. We investigated in healthy subjects the safety, and pharmacokinetics of a liquid service formulation (LSF) and immediate release (IR) tablet of emodepside in 2 randomised, parallel‐group, placebo‐controlled, Phase I studie...

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Detalles Bibliográficos
Autores principales: Gillon, Jean‐Yves, Dennison, Jeremy, van den Berg, Frans, Delhomme, Sophie, Dequatre Cheeseman, Karen, Peña Rossi, Claudia, Strub Wourgaft, Nathalie, Specht, Sabine, Pedrique, Belén, Monnot, Frédéric, Skrabs, Susanne, Rodriguez, Maria‐Luisa, Stass, Heino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518114/
https://www.ncbi.nlm.nih.gov/pubmed/33759250
http://dx.doi.org/10.1111/bcp.14816

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