A polydopamine nanomedicine used in photothermal therapy for liver cancer knocks down the anti-cancer target NEDD8-E3 ligase ROC1 (RBX1)

Knocking down the oncogene ROC1 with siRNA inhibits the proliferation of cancer cells by suppressing the Neddylation pathway. However, methods for delivering siRNA in vivo to induce this high anticancer activity with low potential side effects are urgently needed. Herein, a folic acid (FA)-modified...

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Detalles Bibliográficos
Autores principales: Zhang, Zhanxia, Zhang, Junqian, Tian, Jianhui, Li, Hegen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518243/
https://www.ncbi.nlm.nih.gov/pubmed/34654435
http://dx.doi.org/10.1186/s12951-021-01063-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518243/
https://www.ncbi.nlm.nih.gov/pubmed/34654435
http://dx.doi.org/10.1186/s12951-021-01063-4

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