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d-Serine produces antidepressant-like effects in mice through suppression of BDNF signaling pathway and regulation of synaptic adaptations in the nucleus accumbens

OBJECTIVE: d-Serine is a crucial endogenous co-agonist of N-methyl-d-aspartate receptors (NMDARs) in the central nervous system and can affect the function of the brain derived neurotrophic factor (BDNF) system, which plays an essential role in modulating synaptic plasticity. The current study aimed...

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Detalles Bibliográficos
Autores principales:	Chen, Zhenzhen, Tang, Zhenyu, Zou, Ke, Huang, Zhihong, Liu, Liuer, Yang, Yuanjian, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518303/ https://www.ncbi.nlm.nih.gov/pubmed/34654365 http://dx.doi.org/10.1186/s10020-021-00389-x

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