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Impaired myelin production due to an intrinsic failure of oligodendrocytes in mTORpathies

AIMS: We aim to evaluate if the myelin pathology observed in epilepsy‐associated focal cortical dysplasia type 2B (FCD2B) and—histologically indistinguishable—cortical tubers of tuberous sclerosis complex (TSC) is primarily related to the underlying malformation or constitutes a secondary phenomenon...

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Detalles Bibliográficos
Autores principales: Gruber, Victoria‐Elisabeth, Lang, Judith, Endmayr, Verena, Diehm, Robert, Pimpel, Birgit, Glatter, Sarah, Anink, Jasper J., Bongaarts, Anika, Luinenburg, Mark J., Reinten, Roy J., van der Wel, Nicole, Larsen, Per, Hainfellner, Johannes A., Rössler, Karl, Aronica, Eleonora, Scholl, Theresa, Mühlebner, Angelika, Feucht, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518586/
https://www.ncbi.nlm.nih.gov/pubmed/34173252
http://dx.doi.org/10.1111/nan.12744

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