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A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition
Chirality, a characteristic tool of molecular recognition in nature, is often a complement of redox active systems. Scientists, in their eagerness to mimic such sophistication, have designed numerous chiral systems based on molecular entities with cavities, such as macrocycles and cages. In an attem...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518621/ https://www.ncbi.nlm.nih.gov/pubmed/34374138 http://dx.doi.org/10.1002/chem.202101801 |
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author | Míguez‐Lago, Sandra Gliemann, Bettina D. Kivala, Milan Cid, María Magdalena |
author_facet | Míguez‐Lago, Sandra Gliemann, Bettina D. Kivala, Milan Cid, María Magdalena |
author_sort | Míguez‐Lago, Sandra |
collection | PubMed |
description | Chirality, a characteristic tool of molecular recognition in nature, is often a complement of redox active systems. Scientists, in their eagerness to mimic such sophistication, have designed numerous chiral systems based on molecular entities with cavities, such as macrocycles and cages. In an attempt to combine chirality and redox‐active species, in this contribution we report the synthesis and detailed characterization of a chiral shape‐persistent molecular cage based on the combination of enantiopure diethynylallenes and electron‐rich bridged triarylamines, also known as N‐heterotriangulenes. Its ability for chiral recognition in solution was revealed through UV/vis titrations with enantiopure helicenes. |
format | Online Article Text |
id | pubmed-8518621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85186212021-10-21 A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition Míguez‐Lago, Sandra Gliemann, Bettina D. Kivala, Milan Cid, María Magdalena Chemistry Communications Chirality, a characteristic tool of molecular recognition in nature, is often a complement of redox active systems. Scientists, in their eagerness to mimic such sophistication, have designed numerous chiral systems based on molecular entities with cavities, such as macrocycles and cages. In an attempt to combine chirality and redox‐active species, in this contribution we report the synthesis and detailed characterization of a chiral shape‐persistent molecular cage based on the combination of enantiopure diethynylallenes and electron‐rich bridged triarylamines, also known as N‐heterotriangulenes. Its ability for chiral recognition in solution was revealed through UV/vis titrations with enantiopure helicenes. John Wiley and Sons Inc. 2021-08-12 2021-09-20 /pmc/articles/PMC8518621/ /pubmed/34374138 http://dx.doi.org/10.1002/chem.202101801 Text en © 2021 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Communications Míguez‐Lago, Sandra Gliemann, Bettina D. Kivala, Milan Cid, María Magdalena A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title | A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title_full | A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title_fullStr | A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title_full_unstemmed | A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title_short | A Chiral Molecular Cage Comprising Diethynylallenes and N‐Heterotriangulenes for Enantioselective Recognition |
title_sort | chiral molecular cage comprising diethynylallenes and n‐heterotriangulenes for enantioselective recognition |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518621/ https://www.ncbi.nlm.nih.gov/pubmed/34374138 http://dx.doi.org/10.1002/chem.202101801 |
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