Pharmacokinetics of Asfotase Alfa in Adult Patients With Pediatric‐Onset Hypophosphatasia

Hypophosphatasia is a rare metabolic disease resulting from variant(s) in the gene‐encoding tissue‐nonspecific isozyme of alkaline phosphatase. In this 13‐week, phase 2a, multicenter, randomized, open‐label, dose‐response study (ClinicalTrials.gov: NCT02797821), the pharmacokinetics of asfotase alfa...

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Detalles Bibliográficos
Autores principales: Pan, Wei‐Jian, Pradhan, Rajendra, Pelto, Ryan, Seefried, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518624/
https://www.ncbi.nlm.nih.gov/pubmed/33822385
http://dx.doi.org/10.1002/jcph.1870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518624/
https://www.ncbi.nlm.nih.gov/pubmed/33822385
http://dx.doi.org/10.1002/jcph.1870

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