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Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis

BACKGROUND: Primary cardiac tumors (PCT) are rare lesions but have the potential to cause significant morbidity if not timely treated. We reviewed our single‐center experience in the surgical treatment of PCT with a focus on the long‐term outcome. METHODS: From 2001 to 2020, 57 consecutive patients...

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Autores principales: Matteucci, Matteo, Ferrarese, Sandro, Mantovani, Vittorio, Ronco, Daniele, Torchio, Federica, Franzosi, Cinzia, Marazzato, Jacopo, De Ponti, Roberto, Lorusso, Roberto, Beghi, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518736/
https://www.ncbi.nlm.nih.gov/pubmed/34254361
http://dx.doi.org/10.1111/jocs.15813
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author Matteucci, Matteo
Ferrarese, Sandro
Mantovani, Vittorio
Ronco, Daniele
Torchio, Federica
Franzosi, Cinzia
Marazzato, Jacopo
De Ponti, Roberto
Lorusso, Roberto
Beghi, Cesare
author_facet Matteucci, Matteo
Ferrarese, Sandro
Mantovani, Vittorio
Ronco, Daniele
Torchio, Federica
Franzosi, Cinzia
Marazzato, Jacopo
De Ponti, Roberto
Lorusso, Roberto
Beghi, Cesare
author_sort Matteucci, Matteo
collection PubMed
description BACKGROUND: Primary cardiac tumors (PCT) are rare lesions but have the potential to cause significant morbidity if not timely treated. We reviewed our single‐center experience in the surgical treatment of PCT with a focus on the long‐term outcome. METHODS: From 2001 to 2020, 57 consecutive patients underwent surgical resection of PCT at our Institution. Data including the demographic characteristics, tumor histology, surgical procedure, and postoperative outcomes were collected and analyzed. RESULTS: Mean age at presentation was 63.6 ± 11.2 years, and 33 (57.9%) of the patients were female. A total of 55 (96.5%) subjects were diagnosed with benign cardiac tumor, while the remaining had malignant tumors. The most common histopathological type was myxoma. All patients survived to hospital discharge. Main postoperative complications were: acute kidney injury (n = 3), sepsis (n = 3), and stroke (n = 2). Mean follow‐up time was 9 ± 5.9 years. Long‐term mortality was 22.8% (13/57). No tumor recurrence was observed among survivors. There was a significant relationship between mortality and pathological characteristics of the tumor, and myxomas had higher survival rates. CONCLUSION: Surgical treatment of PCT is a safe and highly effective strategy associated with excellent short‐term outcomes. Long‐term survival remains poor for primary malignant tumors of the heart.
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spelling pubmed-85187362021-10-21 Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis Matteucci, Matteo Ferrarese, Sandro Mantovani, Vittorio Ronco, Daniele Torchio, Federica Franzosi, Cinzia Marazzato, Jacopo De Ponti, Roberto Lorusso, Roberto Beghi, Cesare J Card Surg Original Articles BACKGROUND: Primary cardiac tumors (PCT) are rare lesions but have the potential to cause significant morbidity if not timely treated. We reviewed our single‐center experience in the surgical treatment of PCT with a focus on the long‐term outcome. METHODS: From 2001 to 2020, 57 consecutive patients underwent surgical resection of PCT at our Institution. Data including the demographic characteristics, tumor histology, surgical procedure, and postoperative outcomes were collected and analyzed. RESULTS: Mean age at presentation was 63.6 ± 11.2 years, and 33 (57.9%) of the patients were female. A total of 55 (96.5%) subjects were diagnosed with benign cardiac tumor, while the remaining had malignant tumors. The most common histopathological type was myxoma. All patients survived to hospital discharge. Main postoperative complications were: acute kidney injury (n = 3), sepsis (n = 3), and stroke (n = 2). Mean follow‐up time was 9 ± 5.9 years. Long‐term mortality was 22.8% (13/57). No tumor recurrence was observed among survivors. There was a significant relationship between mortality and pathological characteristics of the tumor, and myxomas had higher survival rates. CONCLUSION: Surgical treatment of PCT is a safe and highly effective strategy associated with excellent short‐term outcomes. Long‐term survival remains poor for primary malignant tumors of the heart. John Wiley and Sons Inc. 2021-07-12 2021-10 /pmc/articles/PMC8518736/ /pubmed/34254361 http://dx.doi.org/10.1111/jocs.15813 Text en © 2021 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals LLC https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Matteucci, Matteo
Ferrarese, Sandro
Mantovani, Vittorio
Ronco, Daniele
Torchio, Federica
Franzosi, Cinzia
Marazzato, Jacopo
De Ponti, Roberto
Lorusso, Roberto
Beghi, Cesare
Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title_full Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title_fullStr Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title_full_unstemmed Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title_short Surgical treatment of primary cardiac tumors in the contemporary era: A single‐centre analysis
title_sort surgical treatment of primary cardiac tumors in the contemporary era: a single‐centre analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518736/
https://www.ncbi.nlm.nih.gov/pubmed/34254361
http://dx.doi.org/10.1111/jocs.15813
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