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The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin

The new class of microbial rhodopsins, called xenorhodopsins (XeRs),([1]) extends the versatility of this family by inward H(+) pumps.([2–4]) These pumps are an alternative optogenetic tool to the light‐gated ion channels (e.g. ChR1,2), because the activation of electrically excitable cells by XeRs...

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Detalles Bibliográficos
Autores principales: Weissbecker, Juliane, Boumrifak, Chokri, Breyer, Maximilian, Wießalla, Tristan, Shevchenko, Vitaly, Mager, Thomas, Slavov, Chavdar, Alekseev, Alexey, Kovalev, Kirill, Gordeliy, Valentin, Bamberg, Ernst, Wachtveitl, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518763/
https://www.ncbi.nlm.nih.gov/pubmed/34339559
http://dx.doi.org/10.1002/anie.202103882