Molecular Basis for Two Stereoselective Diels–Alderases that Produce Decalin Skeletons

Enzymes catalyzing [4+2] cycloaddition have attracted increasing attention because of their key roles in natural product biosynthesis. Here, we solved the X‐ray crystal structures of a pair of decalin synthases, Fsa2 and Phm7, that catalyze intramolecular [4+2] cycloadditions to form enantiomeric de...

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Detalles Bibliográficos
Autores principales: Fujiyama, Keisuke, Kato, Naoki, Re, Suyong, Kinugasa, Kiyomi, Watanabe, Kohei, Takita, Ryo, Nogawa, Toshihiko, Hino, Tomoya, Osada, Hiroyuki, Sugita, Yuji, Takahashi, Shunji, Nagano, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518865/
https://www.ncbi.nlm.nih.gov/pubmed/34121297
http://dx.doi.org/10.1002/anie.202106186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518865/
https://www.ncbi.nlm.nih.gov/pubmed/34121297
http://dx.doi.org/10.1002/anie.202106186

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