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Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents

BACKGROUND: Current treatment options for onchocerciasis are sub-optimal, prompting research and development of a safe cure (macrofilaricide). Onchocerca ochengi, a parasite of cattle, is used as a close surrogate for the human parasite O. volvulus in a murine model for pre-clinical screening of mac...

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Detalles Bibliográficos
Autores principales:	Akumtoh, Desmond N., Njouendou, Abdel J., Metuge, Haelly M., Sjoberg, Hanna T., Pionnier, Nicolas P., Chunda, Valerine C., Gandjui, Narcisse Victor T., Ndzeshang, Lontum B., Fombad, Fanny F., Abong, Raphael A., Enyong, Peter A., Fru-Cho, Jerome, Esum, Mathias E., Ritter, Manuel, Taylor, Mark J., Turner, Joseph D., Wanji, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518880/ https://www.ncbi.nlm.nih.gov/pubmed/34437906 http://dx.doi.org/10.1016/j.exppara.2021.108143

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