Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach

The supramolecular detection by image analysis of a simulant chemical warfare agent on a solid device containing a selective molecular sensor based on a BODIPY scaffold is reported. The recognition properties were investigated in solution, demonstrating high affinity (log K 6.60) and sensitivity (LO...

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Autores principales: Tuccitto, Nunzio, Catania, Gaetano, Pappalardo, Andrea, Trusso Sfrazzetto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518932/
https://www.ncbi.nlm.nih.gov/pubmed/34414611
http://dx.doi.org/10.1002/chem.202102094
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author Tuccitto, Nunzio
Catania, Gaetano
Pappalardo, Andrea
Trusso Sfrazzetto, Giuseppe
author_facet Tuccitto, Nunzio
Catania, Gaetano
Pappalardo, Andrea
Trusso Sfrazzetto, Giuseppe
author_sort Tuccitto, Nunzio
collection PubMed
description The supramolecular detection by image analysis of a simulant chemical warfare agent on a solid device containing a selective molecular sensor based on a BODIPY scaffold is reported. The recognition properties were investigated in solution, demonstrating high affinity (log K 6.60) and sensitivity (LOD 10 ppt). A test strip also confirmed the sensing properties in gas phase. Image analysis of the solid device allows quantitative information about the simulant to be obtained, recovering the sensor almost 5 times and thus confirming the goal of the supramolecular approach.
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spelling pubmed-85189322021-10-21 Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach Tuccitto, Nunzio Catania, Gaetano Pappalardo, Andrea Trusso Sfrazzetto, Giuseppe Chemistry Communications The supramolecular detection by image analysis of a simulant chemical warfare agent on a solid device containing a selective molecular sensor based on a BODIPY scaffold is reported. The recognition properties were investigated in solution, demonstrating high affinity (log K 6.60) and sensitivity (LOD 10 ppt). A test strip also confirmed the sensing properties in gas phase. Image analysis of the solid device allows quantitative information about the simulant to be obtained, recovering the sensor almost 5 times and thus confirming the goal of the supramolecular approach. John Wiley and Sons Inc. 2021-08-20 2021-10-01 /pmc/articles/PMC8518932/ /pubmed/34414611 http://dx.doi.org/10.1002/chem.202102094 Text en © 2021 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Communications
Tuccitto, Nunzio
Catania, Gaetano
Pappalardo, Andrea
Trusso Sfrazzetto, Giuseppe
Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title_full Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title_fullStr Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title_full_unstemmed Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title_short Agile Detection of Chemical Warfare Agents by Machine Vision: a Supramolecular Approach
title_sort agile detection of chemical warfare agents by machine vision: a supramolecular approach
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518932/
https://www.ncbi.nlm.nih.gov/pubmed/34414611
http://dx.doi.org/10.1002/chem.202102094
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