Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids

We describe the synthesis and biological evaluation of a new natural product‐inspired compound class obtained by combining the conceptually complementary pseudo‐natural product (pseudo‐NP) design strategy and a formal adaptation of the complexity‐to‐diversity ring distortion approach. Fragment‐sized...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Flegel, Jana, Otte, Felix, Pahl, Axel, Sievers, Sonja, Strohmann, Carsten, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518946/
https://www.ncbi.nlm.nih.gov/pubmed/34297473
http://dx.doi.org/10.1002/anie.202106654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518946/
https://www.ncbi.nlm.nih.gov/pubmed/34297473
http://dx.doi.org/10.1002/anie.202106654

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