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Fiber modifications enable fowl adenovirus 4 vectors to transduce human cells

BACKGROUND: Pre‐existing immunities hamper the application of human adenovirus (HAdV) vectors in gene therapy or vaccine development. Fowl adenovirus (FAdV)‐based vector might represent an alternative. METHODS: An intermediate plasmid containing FAdV‐4 fiber genes, pMD‐FAV4Fs, was separated from FAd...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenfeng, Guo, Xiaojuan, Yin, Fengcai, Zou, Xiaohui, Hou, Wenzhe, Lu, Zhuozhuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518954/ https://www.ncbi.nlm.nih.gov/pubmed/34050587 http://dx.doi.org/10.1002/jgm.3368

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