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Fiber modifications enable fowl adenovirus 4 vectors to transduce human cells
BACKGROUND: Pre‐existing immunities hamper the application of human adenovirus (HAdV) vectors in gene therapy or vaccine development. Fowl adenovirus (FAdV)‐based vector might represent an alternative. METHODS: An intermediate plasmid containing FAdV‐4 fiber genes, pMD‐FAV4Fs, was separated from FAd...
Autores principales: | Zhang, Wenfeng, Guo, Xiaojuan, Yin, Fengcai, Zou, Xiaohui, Hou, Wenzhe, Lu, Zhuozhuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518954/ https://www.ncbi.nlm.nih.gov/pubmed/34050587 http://dx.doi.org/10.1002/jgm.3368 |
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