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Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses

BACKGROUND: First‐generation cephalosporins have good activity against gram‐positive bacteria and are extensively used in horses. There are few reports of pharmacokinetics and pharmacodynamics (PK/PD) analysis of cephalosporins in horses. OBJECTIVE: To optimise the dosages of the two first‐generatio...

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Detalles Bibliográficos
Autores principales:	Kuroda, Taisuke, Minamijima, Yohei, Niwa, Hidekazu, Tamura, Norihisa, Mita, Hiroshi, Fukuda, Kentaro, Kaimachi, Masahiro, Suzuki, Yuto, Enoki, Yuki, Taguchi, Kazuaki, Matsumoto, Kazuaki, Toutain, Pierre‐Louis, Bousquet‐Melou, Alain, Kasashima, Yoshinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Experimental and Basic Research Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518962/ https://www.ncbi.nlm.nih.gov/pubmed/33341979 http://dx.doi.org/10.1111/evj.13406

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