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Conserved residues Glu37 and Trp229 play an essential role in protein folding of β‐lactamase
Evolutionary robustness requires that the number of highly conserved amino acid residues in proteins is minimized. In enzymes, such conservation is observed for catalytic residues but also for some residues in the second shell or even further from the active site. β‐Lactamases evolve in response to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518976/ https://www.ncbi.nlm.nih.gov/pubmed/33792206 http://dx.doi.org/10.1111/febs.15854 |