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A New Dioxazolone for the Synthesis of 1,2‐Aminoalcohols via Iridium(III)‐Catalyzed C(sp(3))−H Amidation

Vicinal aminoalcohols are widespread structural motifs in bioactive molecules. We report the development of a new dioxazolone reagent containing a p‐nitrophenyldifluoromethyl group, which 1. displays a good safety profile; 2. shows a remarkably high reactivity in the oxime‐directed iridium(III)‐cata...

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Detalles Bibliográficos
Autores principales:	Antien, Kevin, Geraci, Andrea, Parmentier, Michael, Baudoin, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519009/ https://www.ncbi.nlm.nih.gov/pubmed/34427390 http://dx.doi.org/10.1002/anie.202110019

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